American Airlines flights to Greenville-Spartanburg

Travellers and cabin class

The best American Airlines flight deals to Greenville

Looking for a last minute deal or the best direct flight? Find the biggest savings on one-way and return trips to Greenville with American Airlines.

Find which Greenville airports American Airlines flies to

Compare routes to Greenville below. You may find an airport to fly into that's cheaper, faster, or easier.

Flying to Greenville-Spartanburg with American Airlines

The things to know before you go.
Cheapest month to flyApril

Flying to Greenville-Spartanburg with American Airlines: FAQs

American Airlines currently also flies to Dallas Fort Worth International, Chicago O'Hare International and Charlotte Douglas.